Where ever you may travel in the developing world, you'll probably encounter children asking for handouts. Or you may arrive at a country ready to hand out candies/pens/toys.
We STRONGLY recommend that you give your donations to parents, village chiefs, clinics, orphanages, schools, or anywhere that adults can make decisions about the best use of your donations.
Here is a great article with some advice along these lines: http://www.ethicaltraveler.org/fistful.php